LncRNA HOTAIR facilitates proliferation and represses apoptosis of retinoblastoma cells through the miR-20b-5p/RRM2/PI3K/AKT axis

PURPOSE: Retinoblastoma (RB) represents an adolescent eye malignancy. Long non-coding RNA (LncRNA) HOTAIR shows aberrant expression in many malignancies. This research investigated the mechanism of HOTAIR in RB. METHODS: Normal retinal cell lines (ARPE-19 and RPE-1) and RB cell lines (ORB50, Y79, HX...

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Detalles Bibliográficos
Autores principales: Fu, Ke, Zhang, Ke, Zhang, Xiaoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898492/
https://www.ncbi.nlm.nih.gov/pubmed/35248107
http://dx.doi.org/10.1186/s13023-022-02206-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898492/
https://www.ncbi.nlm.nih.gov/pubmed/35248107
http://dx.doi.org/10.1186/s13023-022-02206-y

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