Cargando…

LncRNA HOTAIR facilitates proliferation and represses apoptosis of retinoblastoma cells through the miR-20b-5p/RRM2/PI3K/AKT axis

PURPOSE: Retinoblastoma (RB) represents an adolescent eye malignancy. Long non-coding RNA (LncRNA) HOTAIR shows aberrant expression in many malignancies. This research investigated the mechanism of HOTAIR in RB. METHODS: Normal retinal cell lines (ARPE-19 and RPE-1) and RB cell lines (ORB50, Y79, HX...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fu, Ke, Zhang, Ke, Zhang, Xiaoyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898492/ https://www.ncbi.nlm.nih.gov/pubmed/35248107 http://dx.doi.org/10.1186/s13023-022-02206-y

Ejemplares similares

LncRNA HOTAIR/miR‐613/c‐met axis modulated epithelial‐mesenchymal transition of retinoblastoma cells
por: Yang, Ge, et al.
Publicado: (2018)

Functions of lncRNA HOTAIR in lung cancer
por: Loewen, Gregory, et al.
Publicado: (2014)

lncRNA HOTAIR functions and therapeutic perspectives
por: Garbo, Sabrina, et al.
Publicado: (2022)

LncRNA HOTAIR in Tumor Microenvironment: What Role?
por: Botti, Gerardo, et al.
Publicado: (2019)

Functional polymorphisms in LncRNA HOTAIR contribute to susceptibility of pancreatic cancer
por: Jiang, Dawei, et al.
Publicado: (2019)

Genetic variants of lncRNA HOTAIR contribute to the risk of osteosarcoma
por: Zhou, Quan, et al.
Publicado: (2016)

LncRNA PACER is down-regulated in osteoarthritis and regulates chondrocyte apoptosis and lncRNA HOTAIR expression
por: Jiang, Mingwei, et al.
Publicado: (2019)

The lncRNA lincNMR regulates nucleotide metabolism via a YBX1 - RRM2 axis in cancer
por: Gandhi, Minakshi, et al.
Publicado: (2020)

Prognostic Value of LncRNA HOTAIR in Colorectal Cancer: A Meta-analysis
por: Chen, Shuangqian, et al.
Publicado: (2020)

LncRNA‐HOTAIR promotes endothelial cell pyroptosis by regulating the miR‐22/NLRP3 axis in hyperuricaemia
por: Chi, Kun, et al.
Publicado: (2021)

LncRNA HOTAIR regulates the PI3K/AKT pathway via the miR‐126‐3p/PIK3R2 axis to participate in synovial angiogenesis in rheumatoid arthritis
por: Liu, Feifei, et al.
Publicado: (2023)

Knockdown of lncRNA-HOTAIR downregulates the drug-resistance of breast cancer cells to doxorubicin via the PI3K/AKT/mTOR signaling pathway
por: Li, Zhixiang, et al.
Publicado: (2019)

Functions and underlying mechanisms of lncRNA HOTAIR in cancer chemotherapy resistance
por: Zhu, Chunming, et al.
Publicado: (2022)

The lncRNA HOTAIR: a pleiotropic regulator of epithelial cell plasticity
por: Amicone, Laura, et al.
Publicado: (2023)

LncRNA‐HOTAIR promotes endothelial cell pyroptosis by regulating the miR‐22/NLRP3 axis in hyperuricemia
Publicado: (2023)

Exosomal lncRNA HOTAIR induce macrophages to M2 polarization via PI3K/ p-AKT /AKT pathway and promote EMT and metastasis in laryngeal squamous cell carcinoma
por: Wang, Jingting, et al.
Publicado: (2022)

LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer
por: Xue, Xingyang, et al.
Publicado: (2015)

Circulating HOTAIR LncRNA Is Potentially Up-regulated in Coronary Artery Disease
por: Avazpour, Niloofar, et al.
Publicado: (2018)

lncRNA HOTAIR knockdown suppresses gastric cancer cell biological activities
por: Chao, Pan, et al.
Publicado: (2020)

The HOTAIR lncRNA: A remarkable oncogenic promoter in human cancer metastasis
por: Chen, Lili, et al.
Publicado: (2021)

Association between HOTAIR lncRNA Polymorphisms and Coronary Artery Disease Susceptibility
por: Kim, In-Jai, et al.
Publicado: (2021)

The diagnostic value of lncRNA HOTAIR for cervical carcinoma in vaginal discharge and serum
por: Liu, Ming-Yan, et al.
Publicado: (2023)

LncRNA HOTAIR influences cell growth, migration, invasion, and apoptosis via the miR‐20a‐5p/HMGA2 axis in breast cancer
por: Zhao, Wenyan, et al.
Publicado: (2018)

LncRNA PTCSC3 inhibits cell proliferation in laryngeal squamous cell carcinoma by down-regulating lncRNA HOTAIR
por: Xiao, Dong, et al.
Publicado: (2019)

LncRNA HOTAIR epigenetically suppresses miR-122 expression in hepatocellular carcinoma via DNA methylation
por: Cheng, Di, et al.
Publicado: (2018)

Radiosynthesis of a novel antisense imaging probe targeting LncRNA HOTAIR in malignant glioma
por: Ren, Jiongyu, et al.
Publicado: (2022)

FEZF1-AS1 functions as an oncogenic lncRNA in retinoblastoma
por: Quan, Lian-Jiao, et al.
Publicado: (2019)

Long noncoding RNA (lncRNA) HOTAIR: Pathogenic roles and therapeutic opportunities in gastric cancer
por: Kong, Wencheng, et al.
Publicado: (2021)

LncRNA CANT1 suppresses retinoblastoma progression by repellinghistone methyltransferase in PI3Kγ promoter
por: Ni, Hongyan, et al.
Publicado: (2020)

Onco-lncRNA HOTAIR and its functional genetic variants in papillary thyroid carcinoma
por: Zhu, Hui, et al.
Publicado: (2016)

The lncRNA HOTAIR impacts on mesenchymal stem cells via triple helix formation
por: Kalwa, Marie, et al.
Publicado: (2016)

LncRNA HOTAIR regulates lipopolysaccharide-induced cytokine expression and inflammatory response in macrophages
por: Obaid, Monira, et al.
Publicado: (2018)

Osteopontin‐induced lncRNA HOTAIR expression is involved in osteoarthritis by regulating cell proliferation
por: Liang, Quanzhi, et al.
Publicado: (2021)

Investigating the effect of lncRNA HOTAIR on apoptosis induced by myocardial ischemia-reperfusion injury
por: Fang, Jijing, et al.
Publicado: (2021)

Genetic impacts on thermostability of onco-lncRNA HOTAIR during the development and progression of endometriosis
por: Chang, Cherry Yin-Yi, et al.
Publicado: (2021)

LncRNA HOTAIR: A Potential Prognostic Factor and Therapeutic Target in Human Cancers
por: Xin, Xiaoru, et al.
Publicado: (2021)

HOTAIR Facilitates Endocrine Resistance in Breast Cancer Through ESR1/miR-130b-3p Axis: Comprehensive Analysis of mRNA-miRNA-lncRNA Network
por: Zhang, Mingdi, et al.
Publicado: (2021)

LncRNA HOTAIR-mediated MTHFR methylation inhibits 5-fluorouracil sensitivity in esophageal cancer cells
por: Zhang, Shuyao, et al.
Publicado: (2020)

LncRNA HOTAIR Contributes to Sorafenib Resistance through Suppressing miR-217 in Hepatic Carcinoma
por: Tang, Xiaofeng, et al.
Publicado: (2020)

Neohesperidin Ameliorates Steroid-Induced Osteonecrosis of the Femoral Head by Inhibiting the Histone Modification of lncRNA HOTAIR
por: Yuan, Shuai, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_hd3vhlatqjb8nko46n28tpavc7