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Acute inhibition of OGA sex-dependently alters the networks associated with bioenergetics, autophagy, and neurodegeneration

The accumulation of neurotoxic proteins characteristic of age-related neurodegenerative pathologies such as Alzheimer’s and Parkinson’s diseases is associated with the perturbation of metabolism, bioenergetics, and mitochondrial quality control. One approach to exploit these interactions therapeutic...

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Detalles Bibliográficos
Autores principales: Huynh, Van N., Benavides, Gloria A., Johnson, Michelle S., Ouyang, Xiaosen, Chacko, Balu K., Osuma, Edie, Mueller, Toni, Chatham, John, Darley-Usmar, Victor M., Zhang, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898497/
https://www.ncbi.nlm.nih.gov/pubmed/35248135
http://dx.doi.org/10.1186/s13041-022-00906-x