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Acute inhibition of OGA sex-dependently alters the networks associated with bioenergetics, autophagy, and neurodegeneration
The accumulation of neurotoxic proteins characteristic of age-related neurodegenerative pathologies such as Alzheimer’s and Parkinson’s diseases is associated with the perturbation of metabolism, bioenergetics, and mitochondrial quality control. One approach to exploit these interactions therapeutic...
Autores principales: | Huynh, Van N., Benavides, Gloria A., Johnson, Michelle S., Ouyang, Xiaosen, Chacko, Balu K., Osuma, Edie, Mueller, Toni, Chatham, John, Darley-Usmar, Victor M., Zhang, Jianhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898497/ https://www.ncbi.nlm.nih.gov/pubmed/35248135 http://dx.doi.org/10.1186/s13041-022-00906-x |
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