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Exosomes derived from reparative M2-like macrophages prevent bone loss in murine periodontitis models via IL-10 mRNA

BACKGROUND: Periodontitis is characterized by progressive inflammation and alveolar bone loss resulting in tooth loss finally. Macrophages including pro-inflammatory M1-like macrophages and reparative M2-like macrophages play a vital role in inflammation and tissue homeostasis in periodontitis. Amon...

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Detalles Bibliográficos
Autores principales: Chen, Xutao, Wan, Zhuo, Yang, Liu, Song, Shuang, Fu, Zhaoyue, Tang, Kang, Chen, Lihua, Song, Yingliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898524/
https://www.ncbi.nlm.nih.gov/pubmed/35248085
http://dx.doi.org/10.1186/s12951-022-01314-y