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Alpha‐actinin‐4 (ACTN4) gene amplification is a predictive biomarker for adjuvant chemotherapy with tegafur/uracil in stage I lung adenocarcinomas

Although adjuvant tegafur/uracil (UFT) is recommended for patients with completely resected stage I non‐small‐cell lung cancer (NSCLC) in Japan, only one‐third of cases has received adjuvant chemotherapy (ADJ) according to real‐world data. Therefore, robust predictive biomarkers for selecting ADJ or...

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Detalles Bibliográficos
Autores principales: Noro, Rintaro, Honda, Kazufumi, Nagashima, Kengo, Motoi, Noriko, Kunugi, Shinobu, Matsubayashi, Jun, Takeuchi, Susumu, Shiraishi, Hideaki, Okano, Tetsuya, Kashiro, Ayumi, Meng, Xue, Yoshida, Yukihiro, Watanabe, Shunichi, Usuda, Jitsuo, Inoue, Tatsuya, Wilber, Huang, Ikeda, Norihiko, Seike, Masahiro, Gemma, Akihiko, Kubota, Kaoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898703/
https://www.ncbi.nlm.nih.gov/pubmed/34845792
http://dx.doi.org/10.1111/cas.15228