Identification of neurodegeneration indicators and disease progression in metachromatic leukodystrophy using quantitative NMR‐based urinary metabolomics

Metachromatic leukodystrophy (MLD) is a lysosomal storage disease caused by a deficiency of the arylsulfatase A (ARSA). ARSA deficiency leads to an accumulation of sulfatides primarily in the nervous system ultimately causing demyelination. With evolving therapeutic options, there is an increasing n...

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Detalles Bibliográficos
Autores principales: Laugwitz, Lucia, Zizmare, Laimdota, Santhanakumaran, Vidiyaah, Cannet, Claire, Böhringer, Judith, Okun, Jürgen G., Spraul, Manfred, Krägeloh‐Mann, Ingeborg, Groeschel, Samuel, Trautwein, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Research Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898726/
https://www.ncbi.nlm.nih.gov/pubmed/35281658
http://dx.doi.org/10.1002/jmd2.12273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898726/
https://www.ncbi.nlm.nih.gov/pubmed/35281658
http://dx.doi.org/10.1002/jmd2.12273

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