Identification of neurodegeneration indicators and disease progression in metachromatic leukodystrophy using quantitative NMR‐based urinary metabolomics

Metachromatic leukodystrophy (MLD) is a lysosomal storage disease caused by a deficiency of the arylsulfatase A (ARSA). ARSA deficiency leads to an accumulation of sulfatides primarily in the nervous system ultimately causing demyelination. With evolving therapeutic options, there is an increasing n...

Descripción completa

Detalles Bibliográficos
Autores principales: Laugwitz, Lucia, Zizmare, Laimdota, Santhanakumaran, Vidiyaah, Cannet, Claire, Böhringer, Judith, Okun, Jürgen G., Spraul, Manfred, Krägeloh‐Mann, Ingeborg, Groeschel, Samuel, Trautwein, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Research Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898726/
https://www.ncbi.nlm.nih.gov/pubmed/35281658
http://dx.doi.org/10.1002/jmd2.12273

Ejemplares similares

Ejemplares similares