Emodin Alleviates High-Glucose-Induced Pancreatic β-Cell Pyroptosis by Inhibiting NLRP3/GSDMD Signaling

Diabetes mellitus (DM) is a chronic noninfectious disease that is mainly featured by pancreatic β-cell (β-cell) dysfunction and impaired glucose homeostasis. Currently, the pathogenesis of dysfunction of the β-cells in DM remains unclear, and therapeutic approaches to it are limited. Emodin (EMD), a...

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Detalles Bibliográficos
Autores principales: Xing, Yiqian, He, Yuchi, Zhang, Yuan, Wang, Heting, Peng, Sihan, Xie, Chunguang, Kang, Jian, Liu, Ya, Zhang, Xiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898799/
https://www.ncbi.nlm.nih.gov/pubmed/35265148
http://dx.doi.org/10.1155/2022/5276832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898799/
https://www.ncbi.nlm.nih.gov/pubmed/35265148
http://dx.doi.org/10.1155/2022/5276832

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