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Emodin Alleviates High-Glucose-Induced Pancreatic β-Cell Pyroptosis by Inhibiting NLRP3/GSDMD Signaling
Diabetes mellitus (DM) is a chronic noninfectious disease that is mainly featured by pancreatic β-cell (β-cell) dysfunction and impaired glucose homeostasis. Currently, the pathogenesis of dysfunction of the β-cells in DM remains unclear, and therapeutic approaches to it are limited. Emodin (EMD), a...
Autores principales: | Xing, Yiqian, He, Yuchi, Zhang, Yuan, Wang, Heting, Peng, Sihan, Xie, Chunguang, Kang, Jian, Liu, Ya, Zhang, Xiyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898799/ https://www.ncbi.nlm.nih.gov/pubmed/35265148 http://dx.doi.org/10.1155/2022/5276832 |
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