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T Cells and CDDO-Me Attenuate Immunosuppressive Activation of Human Melanoma-Conditioned Macrophages

Melanoma tumors are highly immunogenic, making them an attractive target for immunotherapy. However, many patients do not mount robust clinical responses to targeted therapies, which is attributable, at least in part, to suppression of immune responses by tumor-associated macrophages (TAMs) in the t...

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Detalles Bibliográficos
Autores principales: Torres, Gretel M., Yang, Heetaek, Park, Chanhyuk, Spezza, Paul A., Khatwani, Nikhil, Bhandari, Rajan, Liby, Karen T., Pioli, Patricia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898828/
https://www.ncbi.nlm.nih.gov/pubmed/35265066
http://dx.doi.org/10.3389/fimmu.2022.768753