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T Cells and CDDO-Me Attenuate Immunosuppressive Activation of Human Melanoma-Conditioned Macrophages
Melanoma tumors are highly immunogenic, making them an attractive target for immunotherapy. However, many patients do not mount robust clinical responses to targeted therapies, which is attributable, at least in part, to suppression of immune responses by tumor-associated macrophages (TAMs) in the t...
Autores principales: | Torres, Gretel M., Yang, Heetaek, Park, Chanhyuk, Spezza, Paul A., Khatwani, Nikhil, Bhandari, Rajan, Liby, Karen T., Pioli, Patricia A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898828/ https://www.ncbi.nlm.nih.gov/pubmed/35265066 http://dx.doi.org/10.3389/fimmu.2022.768753 |
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