NPT1220-312, a TLR2/TLR9 Small Molecule Antagonist, Inhibits Pro-Inflammatory Signaling, Cytokine Release, and NLRP3 Inflammasome Activation

Toll-like receptors (TLRs) play a critical role in innate immune system responses to damage-associated molecular patterns (DAMPs) and pathogen-associated molecular patterns (PAMPs). A growing body of evidence suggests that excessive TLR-mediated innate immune system activation can lead to neuronal d...

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Detalles Bibliográficos
Autores principales: Habas, Agata, Reddy Natala, Srinivasa, Bowden-Verhoek, Jon K., Stocking, Emily M., Price, Diana L., Wrasidlo, Wolfgang, Bonhaus, Douglas W., Gill, Martin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898874/
https://www.ncbi.nlm.nih.gov/pubmed/35265316
http://dx.doi.org/10.1155/2022/2337363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898874/
https://www.ncbi.nlm.nih.gov/pubmed/35265316
http://dx.doi.org/10.1155/2022/2337363

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