The calcium-free form of atorvastatin inhibits amyloid-β(1–42) aggregation in vitro

Alzheimer's disease is characterized by the presence of extraneuronal amyloid plaques composed of amyloid-beta (Aβ) fibrillar aggregates in the brains of patients. In mouse models, it has previously been shown that atorvastatin (Ator), a cholesterol-lowering drug, has some reducing effect on th...

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Detalles Bibliográficos
Autores principales: Nedaei, Hadi, Rezaei-Ghaleh, Nasrollah, Giller, Karin, Becker, Stefan, Karami, Leila, Moosavi-Movahedi, Ali Akbar, Griesinger, Christian, Saboury, Ali Akbar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898965/
https://www.ncbi.nlm.nih.gov/pubmed/35104501
http://dx.doi.org/10.1016/j.jbc.2022.101662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898965/
https://www.ncbi.nlm.nih.gov/pubmed/35104501
http://dx.doi.org/10.1016/j.jbc.2022.101662

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