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Systemic levels of the soluble co-inhibitory immune checkpoints, CTLA-4, LAG-3, PD-1/PD-L1 and TIM-3 are markedly increased in basal cell carcinoma

Although co-inhibitory immune checkpoint proteins are primarily involved in promoting cell-cell interactions that suppress adaptive immunity, especially tumor immunity, the soluble cell-free variants of these molecules are also detectable in the circulation of cancer patients where they retain immun...

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Detalles Bibliográficos
Autores principales: Malinga, Nonkululeko Z., Siwele, Shalete C., Steel, Helen C., Kwofie, Luyanda L.I., Meyer, Pieter W.A., Smit, Teresa, Anderson, Ronald, Rapoport, Bernardo L., Kgokolo, Mahlatse C.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898970/
https://www.ncbi.nlm.nih.gov/pubmed/35255355
http://dx.doi.org/10.1016/j.tranon.2022.101384