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Primary Nasal Epithelial Cells as a Surrogate Cell Culture Model for Type-II Alveolar Cells to Study ABCA-3 Deficiency

ATP Binding Cassette Subfamily A Member 3 (ABCA-3) is a lipid transporter protein highly expressed in type-II alveolar (AT-II) cells. Mutations in ABCA3 can result in severe respiratory disease in infants and children. To study ABCA-3 deficiency in vitro, primary AT-II cells would be the cell cultur...

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Detalles Bibliográficos
Autores principales: Shaw, Nicole C., Kicic, Anthony, Fletcher, Sue, Wilton, Stephen D., Stick, Stephen M., Schultz, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899037/
https://www.ncbi.nlm.nih.gov/pubmed/35265641
http://dx.doi.org/10.3389/fmed.2022.827416