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Protocol for generating human immune system mice and hydrodynamic injection to analyze human hematopoiesis in vivo

Human immune system (HIS) mice provide a valuable platform to investigate and modulate human hematopoiesis development in vivo. Here, we describe detailed protocols for the construction of HIS mice, modulation of human hematopoiesis in vivo using hydrodynamic injection of plasmids encoding cytokines...

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Detalles Bibliográficos
Autores principales: Ren, Deshan, Liu, Wei, Ding, Shuai, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899045/
https://www.ncbi.nlm.nih.gov/pubmed/35265863
http://dx.doi.org/10.1016/j.xpro.2022.101217