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Protocol for generating human immune system mice and hydrodynamic injection to analyze human hematopoiesis in vivo
Human immune system (HIS) mice provide a valuable platform to investigate and modulate human hematopoiesis development in vivo. Here, we describe detailed protocols for the construction of HIS mice, modulation of human hematopoiesis in vivo using hydrodynamic injection of plasmids encoding cytokines...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899045/ https://www.ncbi.nlm.nih.gov/pubmed/35265863 http://dx.doi.org/10.1016/j.xpro.2022.101217 |