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Loss of NLRP3 increases bacterial cystitis via IRAKM

BACKGROUND: We attempted to characterize the molecular mechanisms that underpin urinary tract infections using a mouse model of cystitis induced by bacterial infection in a background of NOD-, LRR- and PYD domains-containing protein (NLRP3) deficiency. METHODS: Male NLRP3 knockout (NLRP3(−/−)) and c...

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Detalles Bibliográficos
Autores principales: Sun, Jie, Xia, Lei, Peng, Yubing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899148/
https://www.ncbi.nlm.nih.gov/pubmed/35280657
http://dx.doi.org/10.21037/tau-22-67