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Mcl‐1 inhibition overcomes BET inhibitor resistance induced by low FBW7 expression in breast cancer

While the promise of bromodomains and extraterminal (BET) protein inhibitors (BETis) is emerging in breast cancer (BC) therapy, resistance in these cells to BETis conspicuously curbs their therapeutic potential. FBW7 is an important tumour suppressor. However, the role of FBW7 in BC is not clear. In...

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Detalles Bibliográficos
Autores principales: Wang, Xu, Wei, Xiaolin, Cao, Yu, Xing, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899162/
https://www.ncbi.nlm.nih.gov/pubmed/35132755
http://dx.doi.org/10.1111/jcmm.17210