Cargando…

Simvastatin inhibits stem cell proliferation in human leiomyoma via TGF‐β3 and Wnt/β‐Catenin pathways

Uterine leiomyoma (UL) is the most common gynaecologic tumour, affecting an estimated 70 to 80% of women. Leiomyomas develop from the transformation of myometrial stem cells into leiomyoma stem (or tumour‐initiating) cells. These cells undergo self‐renewal and differentiation to mature cells, both a...

Descripción completa

Detalles Bibliográficos
Autores principales: Afrin, Sadia, Ali, Mohamed, El Sabeh, Malak, Yang, Qiwei, Al‐Hendy, Ayman, Borahay, Mostafa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899165/
https://www.ncbi.nlm.nih.gov/pubmed/35118811
http://dx.doi.org/10.1111/jcmm.17211