4‐octyl Itaconate inhibits lipopolysaccharide (LPS)‐induced osteoarthritis via activating Nrf2 signalling pathway

Small molecule drug intervention for chondrocytes is a valuable method for the treatment of osteoarthritis (OA). The 4‐octyl itaconate (OI) is a cellular derivative of itaconate with sound cell permeability and transformation rate. We attempted to confirm the protective role of OI in chondrocytes an...

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Detalles Bibliográficos
Autores principales: Zhang, Qingchen, Bai, Xiaohui, Wang, Rongrong, Zhao, Hao, Wang, Lili, Liu, Jingwen, Li, Ming, Chen, Zheng, Wang, Zejun, Li, Lianxin, Wang, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899168/
https://www.ncbi.nlm.nih.gov/pubmed/35068055
http://dx.doi.org/10.1111/jcmm.17185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899168/
https://www.ncbi.nlm.nih.gov/pubmed/35068055
http://dx.doi.org/10.1111/jcmm.17185

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