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The Amino Terminal Domain and Modulation of Connexin36 Gap Junction Channels by Intracellular Magnesium Ions

Electrical synapses between neurons in the mammalian CNS are predominantly formed of the connexin36 (Cx36) gap junction (GJ) channel protein. Unique among GJs formed of a number of other members of the Cx gene family, Cx36 GJs possess a high sensitivity to intracellular Mg(2+) that can robustly act...

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Detalles Bibliográficos
Autores principales: Kraujalis, Tadas, Gudaitis, Lukas, Kraujaliene, Lina, Snipas, Mindaugas, Palacios-Prado, Nicolás, Verselis, Vytas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899287/
https://www.ncbi.nlm.nih.gov/pubmed/35264979
http://dx.doi.org/10.3389/fphys.2022.839223