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The Dynamic Instability of the Aneuploid Genome

Proper partitioning of replicated sister chromatids at each mitosis is crucial for maintaining cell homeostasis. Errors in this process lead to aneuploidy, a condition in which daughter cells harbor genome imbalances. Importantly, aneuploid cells often experience DNA damage, which in turn could driv...

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Detalles Bibliográficos
Autores principales: Garribba, Lorenza, Santaguida, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899291/
https://www.ncbi.nlm.nih.gov/pubmed/35265623
http://dx.doi.org/10.3389/fcell.2022.838928