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The Dynamic Instability of the Aneuploid Genome
Proper partitioning of replicated sister chromatids at each mitosis is crucial for maintaining cell homeostasis. Errors in this process lead to aneuploidy, a condition in which daughter cells harbor genome imbalances. Importantly, aneuploid cells often experience DNA damage, which in turn could driv...
Autores principales: | Garribba, Lorenza, Santaguida, Stefano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899291/ https://www.ncbi.nlm.nih.gov/pubmed/35265623 http://dx.doi.org/10.3389/fcell.2022.838928 |
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