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PLHPP2 inhibits the stemness of colorectal cancer by inactivating the Nrf2 signaling pathway

Pleckstrin homology (PH) domain leucine-rich repeat protein phosphatase 2 (PHLPP2) is a critical regulator of cellular homeostasis and acts as a tumor suppressor in multiple human cancers. However, its exact biological function in colorectal cancer (CRC) and the underlying molecular mechanism remain...

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Detalles Bibliográficos
Autores principales: Yongfu, Xiong, He, Zhou, Xujian, Huang, Jiemei, Huang, Gang, Yang, Lei, Zhixiong, Jingdong, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899387/
https://www.ncbi.nlm.nih.gov/pubmed/35281874
http://dx.doi.org/10.7150/jca.65444