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Fyn and TOM1L1 are recruited to clathrin-coated pits and regulate Akt signaling

The epidermal growth factor (EGF) receptor (EGFR) controls many aspects of cell physiology. EGF binding to EGFR elicits the membrane recruitment and activation of phosphatidylinositol-3-kinase, leading to Akt phosphorylation and activation. Concomitantly, EGFR is recruited to clathrin-coated pits (C...

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Detalles Bibliográficos
Autores principales: Cabral-Dias, Rebecca, Lucarelli, Stefanie, Zak, Karolina, Rahmani, Sadia, Judge, Gurjeet, Abousawan, John, DiGiovanni, Laura F., Vural, Dafne, Anderson, Karen E., Sugiyama, Michael G., Genc, Gizem, Hong, Wanjin, Botelho, Roberto J., Fairn, Gregory D., Kim, Peter K., Antonescu, Costin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899389/
https://www.ncbi.nlm.nih.gov/pubmed/35238864
http://dx.doi.org/10.1083/jcb.201808181