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Fyn and TOM1L1 are recruited to clathrin-coated pits and regulate Akt signaling
The epidermal growth factor (EGF) receptor (EGFR) controls many aspects of cell physiology. EGF binding to EGFR elicits the membrane recruitment and activation of phosphatidylinositol-3-kinase, leading to Akt phosphorylation and activation. Concomitantly, EGFR is recruited to clathrin-coated pits (C...
Autores principales: | Cabral-Dias, Rebecca, Lucarelli, Stefanie, Zak, Karolina, Rahmani, Sadia, Judge, Gurjeet, Abousawan, John, DiGiovanni, Laura F., Vural, Dafne, Anderson, Karen E., Sugiyama, Michael G., Genc, Gizem, Hong, Wanjin, Botelho, Roberto J., Fairn, Gregory D., Kim, Peter K., Antonescu, Costin N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899389/ https://www.ncbi.nlm.nih.gov/pubmed/35238864 http://dx.doi.org/10.1083/jcb.201808181 |
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