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The aryl hydrocarbon receptor contributes to tissue adaptation of intestinal eosinophils in mice

Eosinophils are potent sources of inflammatory and toxic mediators, yet they reside in large numbers in the healthy intestine without causing tissue damage. We show here that intestinal eosinophils were specifically adapted to their environment and underwent substantial transcriptomic changes. Intes...

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Detalles Bibliográficos
Autores principales: Diny, Nicola Laura, Schonfeldova, Barbora, Shapiro, Michael, Winder, Matthew L., Varsani-Brown, Sunita, Stockinger, Brigitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899390/
https://www.ncbi.nlm.nih.gov/pubmed/35238865
http://dx.doi.org/10.1084/jem.20210970