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Calycosin as a Novel PI3K Activator Reduces Inflammation and Fibrosis in Heart Failure Through AKT–IKK/STAT3 Axis

Aim: Inflammation and fibrosis have been shown to be critical factors in heart failure (HF) progression. Calycosin (Cal) is the major active component of Astragalus mongholicus Bunge and has been reported to have therapeutic effects on the cardiac dysfunction after myocardial infarction. However, wh...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoping, Li, Weili, Zhang, Yawen, Sun, Qianbin, Cao, Jing, Tan, NanNan, Yang, Shuangjie, Lu, Linghui, Zhang, Qian, Wei, Peng, Ma, Xiao, Wang, Wei, Wang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899514/
https://www.ncbi.nlm.nih.gov/pubmed/35264961
http://dx.doi.org/10.3389/fphar.2022.828061