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Optogenetic therapy restores retinal activity in primate for at least a year following photoreceptor ablation

All retina-based vision restoration approaches rely on the assumption that photoreceptor loss does not preclude reactivation of the remaining retinal architecture. Whether extended periods of vision loss limit the efficacy of restorative therapies at the retinal level is unknown. We examined long-te...

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Detalles Bibliográficos
Autores principales: McGregor, Juliette E., Kunala, Karteek, Xu, Zhengyang, Murphy, Peter J., Godat, Tyler, Strazzeri, Jennifer M., Bateman, Brittany A., Fischer, William S., Parkins, Keith, Chu, Colin J., Puthussery, Teresa, Williams, David R., Merigan, William H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899524/
https://www.ncbi.nlm.nih.gov/pubmed/34547460
http://dx.doi.org/10.1016/j.ymthe.2021.09.014