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Astrocytic junctional adhesion molecule-A regulates T-cell entry past the glia limitans to promote central nervous system autoimmune attack

Contact-mediated interactions between the astrocytic endfeet and infiltrating immune cells within the perivascular space are underexplored, yet represent potential regulatory check-points against CNS autoimmune disease and disability. Reactive astrocytes upregulate junctional adhesion molecule-A, an...

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Detalles Bibliográficos
Autores principales: Amatruda, Mario, Chapouly, Candice, Woo, Viola, Safavi, Farinaz, Zhang, Joy, Dai, David, Therattil, Anthony, Moon, Chang, Villavicencio, Jorge, Gordon, Alexandra, Parkos, Charles, Horng, Sam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899531/
https://www.ncbi.nlm.nih.gov/pubmed/35265839
http://dx.doi.org/10.1093/braincomms/fcac044