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Single-Cell RNA Sequencing of the Nucleus Pulposus Reveals Chondrocyte Differentiation and Regulation in Intervertebral Disc Degeneration

The nucleus pulposus (NP), a heterogeneous tissue, is an essential functional component of the intervertebral disc. However, NP cell development route and regulation mechanism in intervertebral disc degeneration (IVDD) remain unknown. Here, we performed single-cell RNA sequencing of six NP samples w...

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Detalles Bibliográficos
Autores principales: Han, Shuo, Zhang, Yiran, Zhang, Xianjuan, Zhang, Hao, Meng, Shengwei, Kong, Meng, Liu, Xiaojie, Ma, Xuexiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899542/
https://www.ncbi.nlm.nih.gov/pubmed/35265617
http://dx.doi.org/10.3389/fcell.2022.824771