Claudin-5 binder enhances focused ultrasound-mediated opening in an in vitro blood-brain barrier model

Rationale: The blood-brain barrier (BBB) while functioning as a gatekeeper of the brain, impedes cerebral drug delivery. An emerging technology to overcome this limitation is focused ultrasound (FUS). When FUS interacts with intravenously injected microbubbles (FUS(+MB)), the BBB opens, transiently...

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Detalles Bibliográficos
Autores principales: Chen, Liyu, Sutharsan, Ratneswary, Lee, Jonathan LF, Cruz, Esteban, Asnicar, Blaise, Palliyaguru, Tishila, Wasielewska, Joanna M, Gaudin, Arnaud, Song, Jae, Leinenga, Gerhard, Götz, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899584/
https://www.ncbi.nlm.nih.gov/pubmed/35265192
http://dx.doi.org/10.7150/thno.65539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899584/
https://www.ncbi.nlm.nih.gov/pubmed/35265192
http://dx.doi.org/10.7150/thno.65539

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