Cargando…
Claudin-5 binder enhances focused ultrasound-mediated opening in an in vitro blood-brain barrier model
Rationale: The blood-brain barrier (BBB) while functioning as a gatekeeper of the brain, impedes cerebral drug delivery. An emerging technology to overcome this limitation is focused ultrasound (FUS). When FUS interacts with intravenously injected microbubbles (FUS(+MB)), the BBB opens, transiently...
Autores principales: | Chen, Liyu, Sutharsan, Ratneswary, Lee, Jonathan LF, Cruz, Esteban, Asnicar, Blaise, Palliyaguru, Tishila, Wasielewska, Joanna M, Gaudin, Arnaud, Song, Jae, Leinenga, Gerhard, Götz, Jürgen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899584/ https://www.ncbi.nlm.nih.gov/pubmed/35265192 http://dx.doi.org/10.7150/thno.65539 |
Ejemplares similares
-
A sporadic Alzheimer's blood-brain barrier model for developing ultrasound-mediated delivery of Aducanumab and anti-Tau antibodies
por: Wasielewska, Joanna M., et al.
Publicado: (2022) -
Safety and Efficacy of Scanning Ultrasound Treatment of Aged APP23 Mice
por: Leinenga, Gerhard, et al.
Publicado: (2018) -
Ultrasound-mediated blood-brain barrier opening enhances delivery of therapeutically relevant formats of a tau-specific antibody
por: Janowicz, Phillip W., et al.
Publicado: (2019) -
Fyn nanoclustering requires switching to an open conformation and is enhanced by FTLD-Tau biomolecular condensates
por: Martínez-Mármol, Ramón, et al.
Publicado: (2022) -
Repeated ultrasound treatment of tau transgenic mice clears neuronal tau by autophagy and improves behavioral functions
por: Pandit, Rucha, et al.
Publicado: (2019)