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High Immunogenicity of a T-Cell Epitope-Rich Recombinant Protein Rv1566c-444 From Mycobacterium tuberculosis in Immunized BALB/c Mice, Despite Its Low Diagnostic Sensitivity

The discovery of immunodominant antigens is of great significance for the development of new especially sensitive diagnostic reagents and effective vaccines in controlling tuberculosis (TB). In the present study, we targeted the T-Cell epitope-rich fragment (nucleotide position 109-552) of Rv1566c f...

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Detalles Bibliográficos
Autores principales: Luan, Xiuli, Fan, Xueting, Wang, Ruihuan, Deng, Yunli, Chen, Zixin, Li, Na, Yan, Yuhan, Li, Xiaoyan, Liu, Haican, Li, Guilian, Wan, Kanglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899609/
https://www.ncbi.nlm.nih.gov/pubmed/35265079
http://dx.doi.org/10.3389/fimmu.2022.824415