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Pathological Human Tau Induces Alterations in the Brain Insulin Signaling Cascade
The process of neurodegeneration in Alzheimer’s disease has been associated with a disruption of insulin signaling cascade in neurons, and to insulin resistance. T2DM correlates with Alzheimer’s disease, but mechanisms of interaction are unknown. We have developed a mouse model of tau induced neurod...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899662/ https://www.ncbi.nlm.nih.gov/pubmed/35264925 http://dx.doi.org/10.3389/fnins.2022.805046 |