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RNASE2 Mediates Age-Associated B Cell Expansion Through Monocyte Derived IL-10 in Patients With Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is characterized by the production of pathogenic autoantibodies. Ribonuclease A family member 2 (RNase2) is known to have antiviral activity and immunomodulatory function. Although RNASE2 level has been reported to be elevated in SLE patients based on mRNA microarr...

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Detalles Bibliográficos
Autores principales: Zhu, Yantong, Tang, Xiaojun, Xu, Yang, Wu, Si, Liu, Weilin, Geng, Linyu, Ma, Xiaolei, Tsao, Betty P., Feng, Xuebing, Sun, Lingyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899663/
https://www.ncbi.nlm.nih.gov/pubmed/35265065
http://dx.doi.org/10.3389/fimmu.2022.752189