Cargando…

lncRNA HITT inhibits metastasis by attenuating Rab5-mediated endocytosis in lung adenocarcinoma

Endocytosis of cell surface receptors is essential for cell migration and cancer metastasis. Rab5, a small GTPase of the Rab family, is a key regulator of endosome dynamics and thus cell migration. However, how its activity is regulated still remains to be addressed. Here, we identified a Rab5 inhib...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xingwen, Zheng, Shanliang, Yang, Fan, Zhang, Wenxin, Zhao, Dong, Xue, Xuting, Lin, Qingyu, He, Yunfei, Hu, Guohong, Hu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899701/
https://www.ncbi.nlm.nih.gov/pubmed/35017116
http://dx.doi.org/10.1016/j.ymthe.2022.01.014