Stress-induced tyrosine phosphorylation of RtcB modulates IRE1 activity and signaling outputs

ER stress is mediated by three sensors and the most evolutionary conserved IRE1α signals through its cytosolic kinase and endoribonuclease (RNase) activities. IRE1α RNase activity can either catalyze the initial step of XBP1 mRNA unconventional splicing or degrade a number of RNAs through regulated...

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Detalles Bibliográficos
Autores principales: Papaioannou, Alexandra, Centonze, Federica, Metais, Alice, Maurel, Marion, Negroni, Luc, Gonzalez-Quiroz, Matías, Mahdizadeh, Sayyed Jalil, Svensson, Gabriella, Zare, Ensieh, Blondel, Alice, Koong, Albert C, Hetz, Claudio, Pedeux, Rémy, Tremblay, Michel L, Eriksson, Leif A, Chevet, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899846/
https://www.ncbi.nlm.nih.gov/pubmed/35193953
http://dx.doi.org/10.26508/lsa.202201379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899846/
https://www.ncbi.nlm.nih.gov/pubmed/35193953
http://dx.doi.org/10.26508/lsa.202201379

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