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The NLRP1 Inflammasome Induces Pyroptosis in Human Corneal Epithelial Cells

PURPOSE: Inflammasomes are multiprotein complexes that detect danger-associated signals and trigger an immunostimulatory form of cell death called pyroptosis. NLRP1 is an innate immune receptor that assembles into an inflammasome, but the primary cell types in which NLRP1 is functional have not yet...

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Detalles Bibliográficos
Autores principales: Griswold, Andrew R., Huang, Hsin-Che, Bachovchin, Daniel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899863/
https://www.ncbi.nlm.nih.gov/pubmed/35238869
http://dx.doi.org/10.1167/iovs.63.3.2