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Clinical evaluation of a droplet digital PCR assay for detecting POLE mutations and molecular classification of endometrial cancer

OBJECTIVE: We evaluated droplet digital polymerase chain reaction (ddPCR) method for detecting POLE mutations in endometrial cancer (EC) and guiding its molecular classification. METHODS: We reviewed 240 EC specimens from our hospital database. A ddPCR assay was used to identify POLE mutations at 5...

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Detalles Bibliográficos
Autores principales: Kim, Gilhyang, Lee, Song Kook, Suh, Dong Hoon, Kim, Kidong, No, Jae Hong, Kim, Yong Beom, Kim, Hyojin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asian Society of Gynecologic Oncology; Korean Society of Gynecologic Oncology; Japan Society of Gynecologic Oncology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899877/
https://www.ncbi.nlm.nih.gov/pubmed/34910396
http://dx.doi.org/10.3802/jgo.2022.33.e15