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THEM6‐mediated reprogramming of lipid metabolism supports treatment resistance in prostate cancer

Despite the clinical benefit of androgen‐deprivation therapy (ADT), the majority of patients with advanced prostate cancer (PCa) ultimately develop lethal castration‐resistant prostate cancer (CRPC). In this study, we identified thioesterase superfamily member 6 (THEM6) as a marker of ADT resistance...

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Detalles Bibliográficos
Autores principales: Blomme, Arnaud, Peter, Coralie, Mui, Ernest, Rodriguez Blanco, Giovanny, An, Ning, Mason, Louise M, Jamieson, Lauren E, McGregor, Grace H, Lilla, Sergio, Ntala, Chara, Patel, Rachana, Thiry, Marc, Kung, Sonia H Y, Leclercq, Marine, Ford, Catriona A, Rushworth, Linda K, McGarry, David J, Mason, Susan, Repiscak, Peter, Nixon, Colin, Salji, Mark J, Markert, Elke, MacKay, Gillian M, Kamphorst, Jurre J, Graham, Duncan, Faulds, Karen, Fazli, Ladan, Gleave, Martin E, Avezov, Edward, Edwards, Joanne, Yin, Huabing, Sumpton, David, Blyth, Karen, Close, Pierre, Murphy, Daniel J, Zanivan, Sara, Leung, Hing Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899912/
https://www.ncbi.nlm.nih.gov/pubmed/35014179
http://dx.doi.org/10.15252/emmm.202114764