Natural killer T cell immunotherapy combined with IL-15-expressing oncolytic virotherapy and PD-1 blockade mediates pancreatic tumor regression

BACKGROUND: Pancreatic cancer is one of the leading causes of cancer death, with a 5-year -year survival rate of less than 10%. This results from late detection, high rates of metastasis, and resistance to standard chemotherapies. Furthermore, chemotherapy and radiation are associated with significa...

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Detalles Bibliográficos
Autores principales: Nelson, Adam, Gebremeskel, Simon, Lichty, Brian D, Johnston, Brent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Oncolytic and Local Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900046/
https://www.ncbi.nlm.nih.gov/pubmed/35246474
http://dx.doi.org/10.1136/jitc-2021-003923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900046/
https://www.ncbi.nlm.nih.gov/pubmed/35246474
http://dx.doi.org/10.1136/jitc-2021-003923

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