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Exhibition of antifungal resistance by sterol-auxotrophic strains of Candida glabrata with intact virulence

BACKGROUND: Candida glabrata is an emerging fungal pathogen in immune-compromised hosts. Previously undetected C. glabrata isolates were successfully recovered from clinical specimens by adding sterols to the growth medium. The clinical isolates are unable to synthesize ergosterol but can take up ex...

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Detalles Bibliográficos
Autores principales: Nagi, Minoru, Tanabe, Koichi, Tanaka, Kazuko, Ueno, Keigo, Nakayama, Hironobu, Ishikawa, Jun, Abe, Masahiro, Yamagoe, Satoshi, Umeyama, Takashi, Nakamura, Shigeki, Sugai, Motoyuki, Hazen, Kevin C., Miyazaki, Yoshitsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900151/
https://www.ncbi.nlm.nih.gov/pubmed/35265841
http://dx.doi.org/10.1093/jacamr/dlac018