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Exhibition of antifungal resistance by sterol-auxotrophic strains of Candida glabrata with intact virulence
BACKGROUND: Candida glabrata is an emerging fungal pathogen in immune-compromised hosts. Previously undetected C. glabrata isolates were successfully recovered from clinical specimens by adding sterols to the growth medium. The clinical isolates are unable to synthesize ergosterol but can take up ex...
Autores principales: | Nagi, Minoru, Tanabe, Koichi, Tanaka, Kazuko, Ueno, Keigo, Nakayama, Hironobu, Ishikawa, Jun, Abe, Masahiro, Yamagoe, Satoshi, Umeyama, Takashi, Nakamura, Shigeki, Sugai, Motoyuki, Hazen, Kevin C., Miyazaki, Yoshitsugu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900151/ https://www.ncbi.nlm.nih.gov/pubmed/35265841 http://dx.doi.org/10.1093/jacamr/dlac018 |
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