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DNA Damage and Activation of cGAS/STING Pathway Induce Tumor Microenvironment Remodeling

DNA damage occurs throughout tumorigenesis and development. The immunogenicity of DNA makes it an immune stimulatory molecule that initiates strong inflammatory responses. The cGAS/STING pathway has been investigated as a critical receptor in both exogenous and endogenous DNA sensing to activate the...

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Detalles Bibliográficos
Autores principales:	Shen, Rong, Liu, Disheng, Wang, Xiaoning, Guo, Zhao, Sun, Haonan, Song, Yanfeng, Wang, Degui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900217/ https://www.ncbi.nlm.nih.gov/pubmed/35265630 http://dx.doi.org/10.3389/fcell.2021.828657

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