Donor bone marrow–derived macrophage MHC II drives neuroinflammation and altered behavior during chronic GVHD in mice

Graft-versus-host disease (GVHD) remains the leading cause of nonrelapse mortality after allogeneic stem cell transplantation for hematological malignancies. Manifestations of GVHD in the central nervous system (CNS) present as neurocognitive dysfunction in up to 60% of patients; however, the mechan...

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Detalles Bibliográficos
Autores principales: Adams, Rachael C., Carter-Cusack, Dylan, Shaikh, Samreen N., Llanes, Genesis T., Johnston, Rebecca L., Quaife-Ryan, Gregory, Boyle, Glen, Koufariotis, Lambros T., Möller, Andreas, Blazar, Bruce R., Vukovic, Jana, MacDonald, Kelli P. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900272/
https://www.ncbi.nlm.nih.gov/pubmed/34570880
http://dx.doi.org/10.1182/blood.2021011671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900272/
https://www.ncbi.nlm.nih.gov/pubmed/34570880
http://dx.doi.org/10.1182/blood.2021011671

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