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Donor bone marrow–derived macrophage MHC II drives neuroinflammation and altered behavior during chronic GVHD in mice
Graft-versus-host disease (GVHD) remains the leading cause of nonrelapse mortality after allogeneic stem cell transplantation for hematological malignancies. Manifestations of GVHD in the central nervous system (CNS) present as neurocognitive dysfunction in up to 60% of patients; however, the mechan...
Autores principales: | Adams, Rachael C., Carter-Cusack, Dylan, Shaikh, Samreen N., Llanes, Genesis T., Johnston, Rebecca L., Quaife-Ryan, Gregory, Boyle, Glen, Koufariotis, Lambros T., Möller, Andreas, Blazar, Bruce R., Vukovic, Jana, MacDonald, Kelli P. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900272/ https://www.ncbi.nlm.nih.gov/pubmed/34570880 http://dx.doi.org/10.1182/blood.2021011671 |
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