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Using ZINC08918027 inhibitor to determine Aurora kinase-chromosomal passenger complex isoforms in mouse oocytes

OBJECTIVE: Miscarriages affect 10% of women aged 25–29, and 53% of women over 45. The primary cause of miscarriage is aneuploidy that originated in eggs. The Aurora kinase family has three members that regulate chromosome segregation. Therefore, distinguishing the roles of these isoforms is importan...

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Detalles Bibliográficos
Autores principales: Kratka, Caroline, Drutovic, David, Blengini, Cecilia S., Schindler, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900367/
https://www.ncbi.nlm.nih.gov/pubmed/35255953
http://dx.doi.org/10.1186/s13104-022-05987-4