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Using ZINC08918027 inhibitor to determine Aurora kinase-chromosomal passenger complex isoforms in mouse oocytes
OBJECTIVE: Miscarriages affect 10% of women aged 25–29, and 53% of women over 45. The primary cause of miscarriage is aneuploidy that originated in eggs. The Aurora kinase family has three members that regulate chromosome segregation. Therefore, distinguishing the roles of these isoforms is importan...
Autores principales: | Kratka, Caroline, Drutovic, David, Blengini, Cecilia S., Schindler, Karen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900367/ https://www.ncbi.nlm.nih.gov/pubmed/35255953 http://dx.doi.org/10.1186/s13104-022-05987-4 |
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